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产品展厅
脱氧核糖核酸酶Ⅱ 来源于猪脾(纯化,溶液)
- 品牌:阿拉丁
- 产地:上海
- 货号:D128605
- cas:9025-64-3
- 价格: ¥1645/瓶
- 发布日期: 2022-08-04
- 更新日期: 2024-04-19
产品详请
产地 | 上海 |
品牌 | 阿拉丁 |
货号 | D128605 |
产品规格 | 5KU |
CAS编号 | 9025-64-3 |
纯度 | ≥12,000 units/mg protein% |
是否进口 | 否 |
Deoxyribonuclease II from porcine spleen has a molecular weight of 38 kDa. The enzyme is a glycoprotein endonuclease with dimeric structure. Optimum pH range is 4.5-5.0 at ionic strength 0.15 M. Deoxyribonuclease II (Acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA yielding products with 3'-phosphates. It also acts on p-nitrophenylphosphodiesters at pH 5.6-5.9. Bernardi (BBRC, 17, 573, 1971) describes a three stage degradation of native DNA by DNase II.DNase II has been used to treat transformed cells during the purification of β-lactamase. It has also been used for the preparation of adenoma tissue in a study that investigated the effect of somatoprim on growth hormone secretion in human adenoma cell cultures (hSA). Deoxyribonuclease II from bovine spleen has been used in a study that conducted a partial purification of deoxyribonucleases from eggs and liver of Xenopus laevis. Deoxyribonuclease II from bovine spleen has also been used in a study to investigate nucleic acid and protein synthesis of splenic lymphocytes.