联系我们
- 联系人:阿拉丁客服部
- 电 话:400-620-6333
- 传 真:86-21-50323701
- 邮 箱:2547091763@qq.com
- 地 址:上海市浦东新区新金桥路36号上海国际财富中心南塔16F
产品展厅
阿西维辛
- 品牌:阿拉丁
- 产地:上海
- 货号:A134970
- cas:42228-92-2
- 价格: ¥3999/瓶
- 发布日期: 2022-08-04
- 更新日期: 2024-04-19
产品详请
产地 | 上海 |
品牌 | 阿拉丁 |
货号 | A134970 |
产品规格 | 10mg |
CAS编号 | 42228-92-2 |
纯度 | 97%% |
是否进口 | 否 |
An inhibitor of GGT used for solid tumor researchAcivicin is an antineoplastic antibiotic believed to act by interfering with glutamine metabolism which has been administered for research in a variety of solid tumors. Bone marrow depression and central neurotoxicity has been observed to sμggest that it may be dose-limiting. Acivicin is an irreversible inhibitor of GGT (γ-glutamyl transpeptidase) ID50 = 0.54 mM. Additionally, it inhibits the enzymatic conversion of leukotriene C4 to leukotriene D4 and the bioactivation and release of nitric oxide from GSNO6. Also, the product displays anti tumor and anti-metastatic activity and blocks H. Pylori GGT-induced T-cell inhibition.